raise a glass

Houston hangover pill startup seen on Shark Tank toasts a new direction

Brooks Powell Thrive Plus Cheers hangover cure

Brooks Powell's innovative pills are said to cure your hangover.

Photo courtesy of Cheers

When Brooks Powell's Houston-based startup got passed over by the investors on Shark Tank last year, he didn't let it deter him. Instead, the Houston entrepreneur buckled down and started seeking investments off the screen.

It paid off, and Cheers (née Thrive+) recently closed a $2.1 million seed round. The round was lead by NextView Ventures, which has the likes of TaskRabbit, threadUP, and Letgo among its portfolio.

With the new investment, Brooks says the company is rebranding from Thrive, its original moniker, to Cheers.

"Thrive+ doesn't really say anything about what we did or who we are about," Powell says. "We knew we needed something fitting for the alcohol industry but at the same time has the connotation of fun, responsibility, and health."

The process has been daunting, but worth it, Powell says, citing companies like Ring, which changed its company name from Doorbot.

"It would be hard to imagine Amazon buying a company named Doorbot," Powell says.

It's worth noting that Doorbot rebranded also following a similar rejection on Shark Tank.

Once Cheers had its new name, Powell began the process of the transition — relabeling bottles, redoing marketing materials, etc. There's still a long road ahead for the rebranding, but Powell says he wasn't going to drag his feet, since the change would just become more expensive and more challenging. Ring, for instance, had to pay $1 million for its new domain name.

"We wanted to become Cheers as soon as possible, because it would only become harder as time went on," he says.

From student to CEO
Cheers' formula isn't new. The key ingredient, Dihydromyricetin, a natural extract — like caffeine to coffee, which made the FDA process smooth sailing. DHM started being identified as an anti-alcohol treatment in 2012 following experiments on the effects on rats.

Around that time, Powell was a sophomore at Princeton University, and he came across the science surrounding DHM and knew if he could harness the natural extract for commercial use, it'd change the game of hangover health.

"I started working with some of my professors and asking them if it was safe and would it be effective," Powell says.

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For more on Cheers and its growth to new markets and what's next, continue reading on InnovationMap.

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Best in class

2 Houston schools lead 2025 rankings for top entrepreneurship programs

Rice University, aerial, campus, buildings

Photo courtesy of Rice University

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Rice University and the University of Houston have topped The Princeton Review and Entrepreneur’s lists of the best graduate and undergraduate schools for entrepreneurship studies for 2025.

Neither school is a stranger to the prestigious national rankings.

Rice ranks first in the graduate category for the sixth consecutive year, and UH ranks first in the undergraduate category for the sixth consecutive year.

“At Rice Business, our students learn both inside and outside the classroom, drawing on our strong industry and community connections in Houston and beyond,” says Peter Rodriguez, dean of Rice’s Jones Graduate School of Business, in a release. “With small class sizes and tailored programs, we aim to equip our students with the skills to create new ventures and excel in a fast-changing business landscape.”

UH President Renu Khator praises the ranking as recognition for the impact of the Cyvia and Melvyn Wolff Center for Entrepreneurship at the C.T. Bauer College of Business.

“This program is a tremendous asset not only to the University of Houston and the Bauer College of Business, but also to the city of Houston, where entrepreneurship fuels both socioeconomic mobility and economic growth,” Khator says in a release. “We are proud to see the impact of this program reverberate throughout our community.”

Rankings for The Princeton Review and Entrepreneur’s 2025 lists were based on a survey of administrators at nearly 300 schools in the U.S., Canada, and Europe that offer entrepreneurship studies. Among the more than 40 factors used for the rankings were academic programs, faculty credentials, mentorship opportunities, and alumni entrepreneurship ventures.

The only other school in Texas that made either top-10 was the University of Texas at Austin.

The top 10 schools on the list of 50 best graduate schools for entrepreneurship studies in 2025 are:

1. Rice University
2. University of California-Los Angeles
3. University of Michigan-Ann Arbor
4. Washington University in St. Louis
5. Babson College
6. University of Washington
7. University of Texas at Austin
8. University of Virginia
9. Erasmus University Rotterdam in the Netherlands
10. University of South Florida

The top 10 schools on the list of 50 best undergraduate schools for entrepreneurship studies in 2025 are:

1. University of Houston
2. University of Texas at Austin
3. Babson College
4. University of Washington
5. Washington University in St. Louis
6. University of Michigan-Ann Arbor
7. University of Maryland-College Park
8. Miami University of Ohio
9. Tecnológico de Monterrey in Mexico
10. Northeastern University

The spirit of entrepreneurship is strong in Houston. The city recently ranked No. 7 on a list of the of the 10 best U.S. cities for entrepreneurs to live.

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The story originally was published on our sister site, InnovationMap.

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