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    raise a glass

    Houston hangover pill startup seen on Shark Tank toasts a new direction

    Natalie Harms, InnovationMap
    Feb 14, 2019 | 4:10 pm
    Brooks Powell Thrive Plus Cheers hangover cure
    Brooks Powell's innovative pills are said to cure your hangover.
    Photo courtesy of Cheers

    When Brooks Powell's Houston-based startup got passed over by the investors on Shark Tank last year, he didn't let it deter him. Instead, the Houston entrepreneur buckled down and started seeking investments off the screen.

    It paid off, and Cheers (née Thrive+) recently closed a $2.1 million seed round. The round was lead by NextView Ventures, which has the likes of TaskRabbit, threadUP, and Letgo among its portfolio.

    With the new investment, Brooks says the company is rebranding from Thrive, its original moniker, to Cheers.

    "Thrive+ doesn't really say anything about what we did or who we are about," Powell says. "We knew we needed something fitting for the alcohol industry but at the same time has the connotation of fun, responsibility, and health."

    The process has been daunting, but worth it, Powell says, citing companies like Ring, which changed its company name from Doorbot.

    "It would be hard to imagine Amazon buying a company named Doorbot," Powell says.

    It's worth noting that Doorbot rebranded also following a similar rejection on Shark Tank.

    Once Cheers had its new name, Powell began the process of the transition — relabeling bottles, redoing marketing materials, etc. There's still a long road ahead for the rebranding, but Powell says he wasn't going to drag his feet, since the change would just become more expensive and more challenging. Ring, for instance, had to pay $1 million for its new domain name.

    "We wanted to become Cheers as soon as possible, because it would only become harder as time went on," he says.

    From student to CEO
    Cheers' formula isn't new. The key ingredient, Dihydromyricetin, a natural extract — like caffeine to coffee, which made the FDA process smooth sailing. DHM started being identified as an anti-alcohol treatment in 2012 following experiments on the effects on rats.

    Around that time, Powell was a sophomore at Princeton University, and he came across the science surrounding DHM and knew if he could harness the natural extract for commercial use, it'd change the game of hangover health.

    "I started working with some of my professors and asking them if it was safe and would it be effective," Powell says.

    ---

    For more on Cheers and its growth to new markets and what's next, continue reading on InnovationMap.

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    a major award

    $2.6 million grant funds UH research towards a fentanyl vaccine

    InnovationMap Staff
    Dec 17, 2025 | 3:15 pm
    Hands holding pill bottle
    Photo by Jellybee on Unsplash
    UH has received a new financial gift towards the Michael C. Gibson Addiction Research Program, which is developing a fentanyl vaccine.

    The estate of Dr. William A. Gibson has granted the University of Houston a $2.6 million gift to support and expand its opioid addiction research, including the development of a fentanyl vaccine that could block the drug's ability to enter the brain.

    The gift builds upon a previous donation from the Gibson estate that honored the scientist’s late son Michael, who died from drug addiction in 2019. The original donation established the Michael C. Gibson Addiction Research Program in UH's department of psychology. The latest donation will establish the Michael Conner Gibson Endowed Professorship in Psychology and the Michael Conner Gibson Research Endowment in the College of Liberal Arts and Social Sciences.

    “This incredibly generous gift will accelerate UH’s addiction research program and advance new approaches to treatment,” Daniel O’Connor, dean of the College of Liberal Arts and Social Sciences, said in a news release.

    The Michael C. Gibson Addiction Research Program is led by UH professor of psychology Therese Kosten and Colin Haile, a founding member of the UH Drug Discovery Institute. Currently, the program produces high-profile drug research, including the fentanyl vaccine.

    According to UH, the vaccine can eliminate the drug’s “high” and could have major implications for the nation’s opioid epidemic, as research reveals Opioid Use Disorder (OUD) is treatable.

    The endowed professorship is combined with a one-to-one match from the Aspire Fund Challenge, a $50 million grant program established in 2019 by an anonymous donor. UH says the program has helped the university increase its number of endowed chairs and professorships, including this new position in the department of psychology.

    “Our future discoveries will forever honor the memory of Michael Conner Gibson and the Gibson family,” O’Connor added in the release. “And I expect that the work supported by these endowments will eventually save many thousands of lives.”

    ----

    This story originally was published on our sister site, InnovationMap.

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