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    65th Season Opener

    Alley's Ether Dome carries extra, sobering punch in the shadow of the TexasMedical Center

    Joseph Campana
    Sep 10, 2011 | 6:24 am
    • John Tyson as Dr. John Warren, from left, Dylan Godwin as George Livingston,Sean Lyons as William Morton, Philip Lehl as Dr. George Hayward, Chris Hutchisonas Dr. Henry Bigelow, and Melissa Pritchett as Elizabeth Whitman Morton (back)in Ether Dome
      Photo by Jann Whaley
    • Michael Bakkensen as Dr. Horace Wells and Elizabeth Bunch as Elizabeth Wells inEther Dome
      Photo by Jann Whaley
    • From left, Michael Bakkensen as Dr. Horace Wells, Elizabeth Bunch as ElizabethWells and Sean Lyons as William Morton in the Alley Theatre's production ofEther Dome
      Photo by Jann Whaley
    • Playwright Elizabeth Egloff
      Photo by Jim Youmans

    In the beginning there was ether.

    Not at the beginning of time, but at the birth of modern anesthesia and commercialized medicine there was ether. This, at least, is how award-winning playwright Elizabeth Egloff sees one of the most important discoveries in the history of medicine.

    The world premiere of her newest play, Ether Dome, opens the Alley Theatre's 65th season with a complex portrait of the human drama behind a medical sea change. Ether Dome started its previews Friday night (with more previews set for Saturday and Sunday) before officially opening on Wednesday for a run that lasts through Oct. 9. Named for the amphitheater at Massachusetts General Hospital in Boston where the uses of ether were first demonstrated, the play is a commission of Hartford Stage and is directed by Michael Wilson.

    Ether may be colorless and tasteless, but its effects were profound. Imagine most surgical procedures with nothing more than opiates and a wooden stick to bite down on. There to usher a simultaneously miraculous and fragile compound, ether, into use in 1865 were a Hartford dentist and a medical student con man, Horace Wells and William Morton respectively, and even more drama than occasioned by modern day health care debates.

    The impact of ether is sobering to consider in the shadow of the Texas Medical Center, an institution itself nearly the same age as the Alley Theatre.

    Wells and Morton weren't exactly the toast of Europe, but readers across the Atlantic couldn't get enough of what is now the disastrous back story to the discovery of the surgical uses of ether. Wells began as Morton's mentor and then became his friend and practically family before Morton, a con man wanted in fourteen states, betrayed him.

    "It started as a student-teacher relationship," Egloff told CultureMap in a recent interview. "It seems to have become a father-student relationship. There was a great love for each other. William betrayed Horace and I think that had something to do with Horace’s addictions and demise."

    Indeed, after Morton successfully demonstrated the uses of ether and claimed credit for its discovery, Wells spiraled into depression, imbalance and addiction before being jailed for throwing sulfuric acid at two prostitutes.

    "Horace was a sensitive idealist," Egloff said, "and Morton was in it for the money. But in the beginning, Morton lived with Horace and was part of the family. Anywhere you look in this play there’s a father-son relationship. We see young men looking for a father figure, and the medical competition destroys the relationship."

    Some believe that the sensational headlines about medical experimentation gone wrong inspired Robert Louis Stevenson's famous novel Dr. Jekyll and Mr. Hyde. "It was a scandal that people couldn't get enough of," Egloff confirmed. "The idea of this doctor experimenting with gas, this very proper doctor turning into a monster and attacking women and killing himself."

    Betrayal may be the motor of human drama in Ether Dome, but for Egloff, it couldn't be more pertinent to contemporary conflicts about the nature and the finance of medical practices.

    "This is the first case of a patent battle, of commercialized medicine," Egloff stated, and of a pharmacist telling a hospital what to do. "By the end of the play, you see the emergence of the modern hospital where the pharmaceutical companies have a lot of control over what doctors can do. Until this time, there was a strict code of ethics. Normally, something this important would have been freely distributed."

    The impact of ether is sobering to consider in the shadow of the Texas Medical Center, an institution itself nearly the same age as the Alley Theatre. Consider that this array of medical institutions covers as much areas as the inner Loop of Chicago, employs nearly 100,000 people, brings $14 billion to the region and logs six million patient visits every year. And it's still growing.

    Egloff might argue all this flows from the discovery of ether. And while this discovery was a godsend for people suffering all manner of ailments, it also implied endless growth.

    " By the end of the play, you see the emergence of the modern hospital where the pharmaceutical companies have a lot of control over what doctors can do," Egloff said.

    "Once ether was worked into the routines of surgery," Egloff explained, "surgery was better and patients got better," she said. "They needed beds so patients should recover. Suddenly, they needed more beds and more supplies and more nurses. Everybody wanted surgery so they needed more doctors. The budgets for these hospitals grew exponentially and they became like businesses."

    Ether was not only a source of professional drama and medical controversy in mid-nineteenth-century America, but it also sparked religious debate. To many, Egloff said, "It didn't seem right to have pain relief. The Bible says you suffer for your sins. Your ability to suffer like Jesus is a measure of your worth as a Christian. That was a tremendous force against using ether. There were doctors spitting like wildfire who would not use it because it went against their ethics."

    A person or an event can emerge as a crossroads not usually recognized until much later in history. Ether Dome tracks the intersection of so many complex issues for contemporary life, it might be subtitled Love Hate Theft Betrayal Innovation Science Medicine God. Maybe in the end, then, ether is most easily understood as a religious mystery. "Even now, anesthesiologists don't know exactly how anesthesia works. They don't have a clear idea of the process, but it seems to work."

    And where would we be without anesthesia? Egloff laughed and said, "I'd be the first person to say, 'Thank God!' "

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    Weekend event planner

    Here are the 14 best things to do in Houston this Christmas weekend

    Craig D. Lindsey
    Dec 24, 2025 | 4:30 pm
    Nutcracker Magical Christmas Ballet
    Photo courtesy of Nutcracker Magical Christmas Ballet
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    So, Thursday is the big day, when many Houstonians will get together with family and/or friends to celebrate Christmas with presents, egg nog, and a festive meal.

    But that doesn’t mean there still won’t be events popping off this weekend. Some are holiday-related (like Stages’ staging of The Twelve Dates of Christmas and the Nutcracker! Magical Christmas Ballet going down in Sugar Land), while others are just some fun things to do (like watching some college football at NRG Stadium or attending the birthday bash of a local punk legend at Dan Electro’s).

    Whatever you do, just have a holly, jolly time this weekend.

    Thursday, December 25

    Toro Toro presents Christmas Brunch
    Embark on a brunch journey over at Toro Toro this Christmas. Executive chef Jonathan Esparza and his team have prepared an extensive, Christmas brunch buffet menu, featuring a selection of traditional holiday dishes and interactive stations. Brunch is priced at $145 per adult and $65 per child (11 and under; children 5 and under eat free). Dinner will also be served a la carte from 5:30 to 10 pm. 10 am.

    Juliet Steakhouse & Fine Dining presents Holiday Buffet Feast
    Juliet will be serving up a fabulous Christmas Day buffet, priced at $59 for adults and $28 for kids 12 and under (children under 5 dine free). The buffet includes carved-to-order turkey and filet mignon, plus sides such as mashed potatoes, green bean casserole, candied yams, cornbread dressing, mac and cheese, collard greens, dinner rolls, Caesar salad, and lobster bisque. Desserts include peach cobbler, sweet potato pie, and assorted cookies. Noon.

    The Flat presents DJ Sun’s A James Brown Christmas Tribute
    DJ Sun will be giving the gift of funk, with The Flat’s annual James Brown musical tribute. Flash Gordon Parks will also be spinning some cuts written, produced, and/or performed by the hardest-working man in show business. Special holiday cocktails will also be served, so pull up and close out Christmas night the right way: by getting funky with it! 8 pm.

    Friday, December 26

    The Museum of Fine Arts, Houston presents Little Kid Flicks and Big Kid Flicks
    A holiday season favorite at the MFAH, Kid Flicks is a compilation of fun, artful, inspired, and thought-provoking short film compilations presented in partnership with the New York International Children’s Film Festival. These award-winning short films offer a chance to explore new frontiers from around the world, across the street, and the ever-expanding boundaries of our own perspectives. Little Kid Flicks is designed for ages 5 and up. Big Kid Flicks is designed for ages 8 and up. 11:30 am and 2 pm.

    Downtown Houston+ presents Movies Under the Stars: The Fighting Temptations
    As part of their Movies Under the Stars series, Downtown Houston+ will present a screening of the 2003 comedy The Fighting Temptations, where our own Beyoncé Knowles-Carter stars as a talented young singer who helps a childhood friend (Cuba Gooding, Jr.) revive a struggling church choir, at Trebly Park. Visitors are encouraged to grab takeout from a surrounding restaurant and bring their own lawn blanket to enjoy the screening. 6:30 pm.

    Improv Houston presents Marcus D. Wiley
    The son of a preacher, Christian comedian (and former Texas Southern University professor) Marcus D. Wiley's charismatic style of delivery is clean, captivating, funny, and knowledgeable. He provides lots of laughter along with a guaranteed message on being a better you. Earlier this year, Wiley released his third, hour-long special Marriage Is Major Surgery (executive-produced by Houston stand-up star Ali Siddiq) on YouTube. 7:30 and 9:45 pm (7 pm Saturday).

    Stages presents The Twelve Dates of Christmas
    After seeing her fiance kiss another woman at the televised Thanksgiving Day Parade, Mary’s life falls apart — just in time for the holidays. Over the next year, she stumbles back into the dating world. It seems nothing can help Mary’s growing cynicism, until the charm and innocence of a five-year-old boy unexpectedly brings a new outlook on life and love. This heartwarming one-woman play offers a hilarious and modern alternative to the old standards of the holiday season. 7:30 pm (3 and 7:30 pm Saturday; 3 pm Sunday).

    Saturday, December 27

    Wonky Power presents Jazz & Jokes
    A new night of stand-up, cocktails, and live jazz will debut inside one of Houston’s most intimate creative rooms. Jazz & Jokes brings together two of the best live experiences — laughter and live music — curated for a cozy, seated evening at Wonky Power. Featuring a rotating cast of special stand-up comedians from Houston and beyond, paired with a live jazz band setting the mood all night, this night will offer a warm, relaxed atmosphere, great drinks, and a room built for performance. 7 pm.

    Kinder's Texas Bowl: Houston vs. LSU
    The 2025 Kinder's Texas Bowl will feature a matchup between the Houston Cougars of the Big 12 Conference, making its 31st all-time bowl appearance, and the LSU Tigers of the Southeastern Conference. Houston enters the Texas Bowl ranked No. 21 in the College Football Playoff rankings with a 9-3 overall record, its best record since 2021. This will mark the first time the Cougars have played in the Bowl since 2007. 8:15 pm.

    The Garden Theatre presents Cruel Intentions
    Based on the 1999 teen flick, Cruel Intentions: The ’90s Musical pulls audiences into the manipulative world of Manhattan’s most dangerous liaisons: Sebastian Valmont and Kathryn Merteuil. Fueled by revenge and passion, the diabolically charming step-siblings place a bet on whether or not Sebastian can deflower their incoming headmaster’s daughter, Annette Hargrove. The musical features throwback hits by artists like Christina Aguilera, 'NSYNC, and Britney Spears. Through Sunday, January 11. 8 pm (2 and 8 pm Saturday; 2 pm Sunday).

    Goode Co. Armadillo Palace presents Roger Creager Piano Bar
    Award-winning country singer/Texas native Roger Creager will be in town to do a post-Xmas set at Goode Co. Armadillo Palace. With more than a dozen No. 1 singles on the Texas Music Chart and Entertainer of the Year honors from both CMA Texas and the Texas Music Awards, Creager brings a mix of road-tested songwriting and bold melodies. Dine on authentic Texas fare, including signature house favorites the Damn Goode Burger and the Damn Goode Margarita. 9 pm.

    Sunday, December 28

    Dan Electro’s presents J.R.’s Birthday Bash
    Houston punk pioneer (and all-around good guy) J.R. Delgado has been a member of multiple punk, hardcore and garage rock bands. He was also the owner of the legendary rock club The Axiom in the late ‘80s and early ‘90s. This weekend, he’lll be celebrating his 70th birthday at Dan Electro’s, and he’ll be having a free throwdown everyone is invited to. Hickoids, Jane Woe, and Bastard Union will be providing the live jams, while DJ LP will be spinning music all day. 1 pm.

    Nutcracker! Magical Christmas Ballet
    |Over at Smart Financial Centre in Sugar Land, Nutcracker! Magical Christmas Ballet will highlight an international cast and Ukrainian principal artists performing at the peak of classical European ballet. Audiences will be transported by the magic of jaw-dropping acrobatics, larger-than-life puppets, and hand-crafted sets and costumes. Share the tradition of pure holiday magic and Tchaikovsky’s timeless score with friends and family of all ages. 3 pm.

    Arthouse Houston presents Hedwig and the Angry Inch with John Cameron Mitchell
    Arthouse Houston will present a one-night-only event of Hedwig and the Angry Inch, with star/creator John Cameron Mitchell. The 2001 indie musical classic (based on Mitchell’s off-Broadway play) follows Hedwig, an East Berliner transplant and lead singer in a band, who is chasing down his ex for stealing his songs. The screening will be accompanied by a live director's commentary by Mitchell, and followed by a live music set led by Mitchell, with band members Amber Martin and Chapman Welch. (Read CultureMap’s exclusive interview with Mitchell here.) 7:30 pm.

    Nutcracker Magical Christmas Ballet
    Photo courtesy of Nutcracker Magical Christmas Ballet

    Nutcracker! Magical Christmas Ballet will perform in Sugar Land this weekend.

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