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    for your health

    Houston hospital creates new breakthrough breast cancer risk tool

    Jillian Goltzman, InnovationMap
    Nov 9, 2020 | 9:15 am
    Houston, Methodist Hospital exterior, August 2017
    A new tool being used at Houston Methodist taps into artificial intelligence breast cancer diagnosis.
    Courtesy of Methodist Hospital/Facebook

    In the medical field, billions of dollars are wasted each year — about $935 billion, but who's counting? According to a paper published by the JAMA Network, an estimated $75.7 billion to $101.2 billion is wasted through overtreatment. Of the many procedures that can lead to wasted resources, breast cancer biopsies are a major source of overtreatment.

    Houston Methodist Hospital is using artificial intelligence to create a more efficient and accurate Breast Cancer Risk Calculator, called iBrisk.

    Breast cancer is something that plagues the lives of many women, and some men. According to the National Breast Cancer Foundation, one in eight women will be diagnosed with breast cancer in their lifetime.

    Women are advised to start having annual mammograms to screen for breast cancer starting at age 40 to try to catch cancer in its earliest stages. With mammograms becoming a standard procedure, the process inevitably leads to more biopsies.

    While more biopsies sound like the obvious course of action, Houston Methodist Hospital shares that out of 10,000 women biopsied, less than two will be positive while using the national standard. The result of a negative biopsy? Wasted time, resources, and money, as well as undue worry for the patient.

    "It's not just wasteful. . .when you do an unnecessary procedure, you're potentially harming the patient," says Stephen Wong, Ph.D. After a negative biopsy, Dr. Wong explains that patients often begin to show emotional responses like high anxiety and low self-esteem. They often speculate the biopsies are wrong, and that they've had a missed cancer diagnosis by their medical provider.

    Dr. Wong estimates that more than 700,000 patients have unnecessary biopsies in the breast cancer category alone.

    Spearheading the iBrisk tool, Dr. Wong has found a way to utilize a smarter model than the current system for detecting breast cancer risk.

    Hospitals across the country currently use the Breast Imaging Reporting and Database System score (BI-RADS), a system created by the American College of Radiology to determine breast cancer risk and biopsy decision-making.

    To expand on BI-RADS data, Dr. Wong used multiple patient data points and AI technology to create the improved system. The iBRISK integrates natural language processing, medical image analysis, and deep learning on multi-modal BI-RADS patient data to make one of three recommendations: biopsy not recommended, consider biopsy, or biopsy recommended.


    "While using AI, we try to simulate how the physician thinks," explains Dr. Wong. "The physician looks at different data: imaging, patient clinical data, demographic, history and other social factors. You don't rely on one particular thing."

    To create iBrisk, Dr. Wong used 12 to 13 years of BI-RAD data at Houston Methodist Hospital to train the AI using deep learning.

    He estimates that more than 80 percent of technical information is in the free text format, meaning unstructured data, in the United States.

    "We applied an AI technique called natural language processing, which is using the computer to read the text automatically for us," explains Dr. Wong.

    This data extraction tool was also used with imaging of mammogram ultrasounds by applying image analysis computer vision.

    iBrisk also deploys deep learning, a machine learning tactic where artificial neural networks, inspired by the human brain, learn from large amounts of data. They determined approximately 100 parameters to analyze, including age, sex, socio-economic data, medical history, and insurance plans. After putting the data points into a deep learning method, the AI reduced the data points to the 20 risk indicators.

    Houston Methodist Hospital used an estimated 11,000 cases for training, and then used 2,200 of its own data to test iBrisk. They have even been able to create unbiased independent validation by working with other hospitals like MD Anderson, testing their patients using iBrisk and confirming the results.

    The potential of iBrisk to cut costs and contribute to less overtreatment has garnered support with other hospitals around the country. The breast cancer risk calculator is a collaboration with Dr. Jenny Chang of HMCC and breast oncologists at MD Anderson, UT San Antonio, and University of Utah Cancer Center.

    While implicit racial bias has become a more prominent issue in the United States, Houston Methodist's iBrisk grants a neutral, unbiased lens. AI isn't immune to racial bias; in fact, computer scientist and founder of the Algorithmic Justice League, Joy Buolamwini, uncovered the large gender and racial biases of AI systems sold by IBM, Amazon and Microsoft in a 2019 article for Time.

    With AI's history of racial bias in mind, Dr. Wong set out to create an impartial, fair system. "Our AI data is not sensitive to race. . .it's unbiased," he explains.

    Houston Methodist Hospital plans to expand the iBrisk model to other forms of cancer in the future, including its next venture into thyroid and incidental lung nodule screenings.

    The AI allows patients to save the stress of getting a biopsy.

    "We are very careful to put any drugs or any procedure into clinical workflow until we are very sure you really have to pick this [outcome]," explains Dr. Wong. Using advanced risk detectors like iBrisk allows medical practitioners to make more thorough, informed decisions for patients looking into biopsies.

    The categories are broken into low, moderate and high-risk groups. The low-risk groups have seen a 99.8 percent accuracy in results, missing only two cases out of a sample of 1,228. Patients that have fallen into the high-risk groups (leading patients to get a biopsy) have seen an 85.9 percent accuracy, compared to radiology, which is 25 percent accurate according to Dr. Wong.

    Dr. Wong notes that patients that fall in the moderate section of the risk assessment can then have a dialogue with their physician to determine if they want to move forward with the biopsy. In the moderate category, there is a 93.4 percent accuracy.

    If implemented, iBrisk would be able to reduce 75 percent of unnecessary biopsies, estimates Dr. Wong.

    Currently, Houston Methodist Hospital is using AI technology outside of oncology, with the recent release of a tool that can diagnose strokes using a smartphone, announced in Science Daily. The tool, which can diagnose abnormalities in a patient's speech and facial muscular movements, was made in collaboration with Dr. Jay Volpi of Eddy Scullock Stroke Center at Houston Methodist Hospital.

    "We are answering bigger questions," explains Dr. Wong, who looks forward to continuing to expand AI capabilities and risk calculators at Houston Methodist Hospital.

    In the future, Dr. Wong looks forward to doing a multicenter trial to bring this technology outside of Texas.

    ---

    This story originally appeared on our sister site, InnovationMap.

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    news/innovation

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    Innovation Station

    Houston company makes Time's best inventions of 2026 list

    John Egan
    Oct 21, 2026 | 9:15 am
    Utility Global H2Gen
    Courtesy of Utility Global
    The H2Gen produces low-cost clean hydrogen.

    One of the year's most buzzworthy innovations has a Houston connection. A new source for clean hydrogen has landed on Time magazine’s list of the 300 best inventions of 2026.

    Houston-based Utility Global made Time’s list with H2Gen, a system that produces low-cost clean hydrogen from water and industrial off-gases. The company says the process doesn’t require electricity, a notable claim since hydrogen production typically consumes a lot of power.

    The startup is on a roll. It has raised $100 million so far in an ongoing Series D round to offer its decarbonization technology at industrial scale around the world.

    Dallas-Fort Worth

    An impressive eight inventions tied to Dallas-Fort Worth — including a phone that blocks nosy neighbors, a self-driving 18-wheeler, and a lab-made egg — also made the list. Here’s a look at the DFW-connected winners, starting with the ones Texans might eventually find in their homes.

    Samsung
    Plano-based Samsung Electronics America pulled off a hat trick this year, with three products making Time’s list.

    First up is the Galaxy S26 Ultra smartphone. It packs a more powerful camera, Galaxy AI features, and pro-level content creation tools. But Time singled out its new built-in privacy display as the phone’s “biggest selling point.” The feature dims the screen when viewed from an angle, making it “nearly impossible” for the person next to you on the plane to read your texts.

    Samsung S26 Ultra smartphone Samsung's Galaxy S26 Ultra smartphone is recognized for its new built-in privacy display.Photo courtesy of Samsung Electronics America/PR Newswire

    Samsung’s Bespoke AI Family Hub refrigerator also got smarter. When AI first came to the Family Hub in 2024, it could recognize some fresh foods, but you still had to log packaged items by hand, Time noted. Now, with Google Gemini built in, the fridge can identify more than 2,000 packaged foods, read handwritten labels, and warn you when food is about to expire. It then uses what’s inside to build grocery lists and suggest recipes, so that half-used jar of pesto might finally see the light of day.

    And for gamers, there’s the Odyssey G8 monitor. Its 6K resolution leapfrogs the 4K standard, delivering what Samsung calls “exceptional visual clarity and detail” on a screen big enough for gaming and multitasking.

    OxeFit
    Plano-based OxeFit’s XS1 Peak is about the size of a treadmill but works like an entire gym. It can be set up for strength training, simulated skiing or kayaking, Pilates, or rowing.

    What makes it stand out is a built-in virtual spotter. According to Time, the machine “uses AI, computer vision and sensors to correct the user’s form, change resistance in the middle of a rep and reduce the weight when the user is struggling, much like a human spotter.”

    When the workout’s done, it folds up against the wall like a Murphy bed. Fair warning: The XS1 Peak retails for more than $6,000.

    EssilorLuxottica
    Parents of nearsighted kids, take note. EssilorLuxottica, the French eyewear giant whose U.S. headquarters is in Farmers Branch, makes Essilor Stellest lenses. The lenses correct nearsightedness while also slowing the eye growth that makes it worse over time.

    Stellest is the first and only eyeglass lens authorized by the U.S. Food and Drug Administration to control myopia, Time said. The lenses look like regular glasses but contain 1,021 tiny lenslets. In a U.S. trial of kids ages 6-12, myopia progression slowed by an average of 71 percent over two years compared with standard lenses.

    Helpany
    If you have a parent or grandparent in senior living, this one may hit home.

    Helpany, a startup based in Phoenix that manufactures its devices in DFW, makes Paul, a ceiling-mounted gadget that uses radar and AI to spot subtle changes in how residents move and flag those at higher risk of falling. Helpany says the technology can cut falls by as much as 72 percent.

    Aurora Innovation
    If you’ve driven I-45 between Dallas and Houston lately, you may have passed a big rig with no one behind the wheel. Last year, Aurora Innovation launched what it calls the country’s first driverless 18-wheeler delivery service on that route.

    Aurora driverless trucks Aurora Innovation's driverless 18-wheeler delivery service travels I-45, between Dallas and Houston. Photo courtesy of Aurora

    Aurora, based in Pittsburgh with a corporate and operations hub in Coppell, rolled out its second-generation Driver 2 system in July. By September, Driver 2 trucks had logged more than 500,000 driverless miles without a single at-fault crash, Time reported, and the company expects 200 of them on the road by the end of 2026. A proprietary sensor lets the trucks see roughly 10 football fields ahead.

    Without a human driver who needs rest, a Fort Worth-to-Phoenix run can take up to 40 percent less time, Time said. “It’s novel. It’s technically extraordinary,” Aurora co-founder and CEO Chris Urmson told Time. “And yet it’s all pretty boring.”

    Aurora operates DFW trucking terminals in Aledo and Palmer.

    Colossal Biosciences
    The list’s most sci-fi DFW entry comes from Dallas-based Colossal Biosciences, the de-extinction company best known for efforts to revive the woolly mammoth and dire wolf.

    Colossal built an artificial egg by placing an ultra-thin, transparent silicone membrane inside a rigid 3D-printed cup, letting scientists watch the embryo develop. Twenty-six chickens have already been hatched.

    Andrew Pask, Colossal’s chief biology officer, told Time the invention could help critically endangered birds — New Zealand’s kākāpō, for example, a flightless parrot that struggles with low hatching rates.

    Austin
    Two companies with ties to the Austin area also landed on the Time list. An Austin company also earned a spot on Time’s “Special Mentions” list.

    Cedar Park-based Hyliion landed on Time’s list with its Karno Power Module, a modular generator designed to produce power wherever it’s needed.

    The Karno represents a big pivot for the company. Hyliion got its start building electrified powertrains for 18-wheelers before shifting into power generation after acquiring the Karno generator technology from GE Aerospace. Founded in Pittsburgh in 2015, the company relocated to Cedar Park in 2018.

    Hyliion recently won a $41.7 million contract from the Office of Naval Research to build 2- and 3-megawatt Karno systems, and trade publication Consulting-Specifying Engineer named the module its 2026 Most Valuable Product.

    The other Austin-associated honoree is Moment Energy. As more electric vehicles hit the road, a growing number of their batteries are nearing retirement, while demand for power keeps climbing. Moment Energy found a way to tackle both problems at once, and the innovation landed it on Time’s list.

    The company’s Megafactory 1, which opened in Vancouver, Canada, in June, turns old EV batteries into modular energy storage systems for hospitals, factories, data centers, and other big power users. “Our goal is to make sure these batteries don’t end up in landfills,” founder Edward Chiang told Time.

    Moment Energy is building a facility in Taylor that will be five times larger, with an opening tentatively set 2028.

    In the “Special Mentions” category, Austin-based Renzoe Box gained notice for its refillable custom makeup palette for on-the-go people. Licensed architect René Graham designed the box. She graduated from Houston's Rice University, and was born and raised in Dallas.

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