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    med center might

    Houston's elite hospitals score No. 1 spots in prestigious new list of best in U.S. and Texas

    Steven Devadanam
    Aug 3, 2022 | 6:15 pm
    MD Anderson cancer center houston
    MD Anderson reigns supreme as the best cancer hospital in the nation.
    Photo by F. Carter Smith/courtesy of MD Anderson

    A prestigious, annual national report has verified what Houstonians already know: Our Medical Center boasts the best adult and children’s hospital in Texas and the best cancer center in America.

    U.S. News & World Report released its 2022-23 Best Hospitals list, which names The University of Texas MD Anderson Cancer Center No. 1 in the nation for cancer care. For those keeping track, MD Anderson has been considered in the top two cancer hospitals in the U.S. since the U.S. News launched the survey in 1990.

    While securing the top rank for cancer care, MD Anderson also scored high national ranks for specialty treatments: urology (No. 5) and diabetes and endocrinology (No. 13). The center continues to maintain its “High Performing” rating on the U.S. News list for colon cancer and lung cancer. It also received “High Performing” ratings for the three newly added adult procedures and conditions: ovarian cancer, prostate cancer, and uterine cancer, per a press release.

    “We are proud to be ranked as the nation’s leader in cancer care,” said Peter WT Pisters, M.D., president of MD Anderson, in a statement. “This ongoing recognition is thanks to the incredible MD Anderson community, including our faculty, employees, trainees, students, donors and advocates, who advance our science and our mission and who serve our patients by enabling us to provide the best care possible.”

    Rankings for the annual U.S. News study are based on scores in patient care, patient safety, outcomes, nursing, advanced technology, and reputation.

    Houston leads medicine in Texas
    The tagline for Houston Methodist Hospital systems — “leading medicine” — is quite fitting here in Texas. The hospital comes in at No. 15 nationally (marking the sixth time it has been recognized in the report’s Honor Roll) and No. 1 in Texas for the 11th year in a row. Locally, Houston Methodist Sugar Land ranks No. 5 in Houston and No. in Texas, a press release notes.

    Notably, U.S. News has ranked Houston Methodist Hospital in at least one specialty for the past 30 years. This year, Houston Methodist Hospital ranks in 10 specialties, the most of any hospital in the state, according to the report. Two of these ranked specialties appear in the list’s top 10 (diabetes and endocrinology at No. 9; gastroenterology/GI surgery at No. 8), while six are ranked in the top 20.

    “This is a tremendous achievement for our physicians and employees who dedicate themselves every day to our patients – especially as we continue to provide the highest quality care during these trying times in health care,” said Marc Boom, M.D., president and CEO of Houston Methodist, in a statement. “Our mission to provide unparalleled care is for our patients, who are the reason we need to be one of the best hospital systems in the country.”

    Texas Children’s tops Texas and Southwest
    Yet another Houston hospital scored extremely well nationally in the list. Texas Children’s Hospital ranks No. 2 overall in the Best Children’s Hospitals ranking. The beloved children’s center also remains top in Texas and the Southwest, and at No. 1 in heart treatment for the sixth year in a row. No other pediatric hospital in Texas has achieved an overall ranking as high as Texas Children’s has in the past 14 years, a Texas Children’s release notes.

    “We are beyond thrilled with the newest U.S. News & World Report rankings that place Texas Children’s Hospital second in the United States and first in the state of Texas,” said Mark A. Wallace, president and CEO, in a statement. “Consistent collaboration, newfound discoveries and extraordinary patient care is what has brought us to where we are today. I am incredibly proud of this remarkable team and everything we’ve accomplished together — and our promise to every family is that we are just getting started.”

    Texas’ best mental health care is here
    Also boasting top honors in the state — and No. 10 nationally — is the Menninger Clinic. The acclaimed facility tied for tenth place on U.S. News’ list of best psychiatric hospitals, making it the all-out best in Texas.

    Of note, Menninger has been named a top-10 psychiatry hospital in the U.S. for 32 consecutive years, the hospital points out. “With the growing need for mental health care, we are grateful for the trust that psychiatrists have had in referring their clients to The Menninger Clinic for comprehensive diagnosis and treatment,” said president and CEO Armando E. Colombo in a statement.

    Elsewhere in Texas
    Dallas-Fort Worth is home to the No. 2 hospital in Texas, per U.S. News. UT Southwestern Medical Center in Dallas also ranked especially well nationally in urology (No. 11), cardiology and heart surgery (No. 14), diabetes and endocrinology (No. 18), pulmonology and lung surgery, (No. 21), and cancer (No. 25).

    Not far down the list is Baylor University Medical Center in Dallas, which ranked No. 4 in Texas. One Baylor department ranked nationally: gastroenterology and GI surgery department, No. 34.

    Meanwhile, Austin’s St. David’s Medical Center ranked No. 8 in Texas. Austinites in need of post-procedure work and physical therapy should note that the hospital’s rehabilitation department ranked nationally, coming in at No. 37 overall.

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    brain scientists at work

    Rice University scientists invent new algorithm to fight Alzheimer's

    Jef Rouner
    Oct 24, 2025 | 3:00 pm
    Vicky Yao and Qiliang Lai of Rice University work on a laptop.
    Photo courtesy of Rice University
    Vicky Yao, an assistant professor of computer science and member of the Ken Kennedy Institute at Rice University, and Qiliang Lai, a Rice postdoctoral researcher

    A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

    Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

    For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

    To prove this link, researchers at Rice alongside Boston University developed a computational algorithm called “Single-cell Expression Integration System for Mapping genetically implicated Cell types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

    “As we age, some brain cells naturally slow down, but in dementia ⎯ a memory-loss disease ⎯ specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

    Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

    “We built our seismic algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

    Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

    “We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

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