Bunny Best met her unfortunate end at a Gay Days parade. Now her two sons, Kyle and Hamilton, have the task of arranging her funeral and carrying for most beloved companion, a troublesome Italian greyhound named Enzo. In the bustle of obituary-writing, eulogy-giving, and dog-sitting, sibling rivalry quickly reaches its peak and years of buried contentions surface.

The Best Brothers is a bittersweet comedy that explores the many ways in which we grieve and the love we find in unexpected places.