Growing up in Chicago, Godfrey constantly got in trouble for misbehaving and being an all-around class clown. Godfrey's Nigerian parents unknowingly encouraged his bad behavior by showing him classic comedy films from an early age. While performing impressions of his college football teammates, Godfrey realized his irreverent style of comedy might be more than just a hobby.

Godfrey has been seen on stages from New York and Los Angeles to Dubai. Along with his own one-hour special on Comedy Central, Godfrey starred in the FX pilot Bronx Warrants, adding to his onscreen credits which include Zoolander, 30 Rock, and a recurring role on Louie. Godfrey also starred alongside Shaquille O'Neal on the TruTV series, Upload.