• Home
  • popular
  • EVENTS
  • submit-new-event
  • CHARITY GUIDE
  • Children
  • Education
  • Health
  • Veterans
  • Social Services
  • Arts + Culture
  • Animals
  • LGBTQ
  • New Charity
  • TRENDING NEWS
  • News
  • City Life
  • Entertainment
  • Sports
  • Home + Design
  • Travel
  • Real Estate
  • Restaurants + Bars
  • Arts
  • Society
  • Innovation
  • Fashion + Beauty
  • subscribe
  • about
  • series
  • Embracing Your Inner Cowboy
  • Green Living
  • Summer Fun
  • Real Estate Confidential
  • RX In the City
  • State of the Arts
  • Fall For Fashion
  • Cai's Odyssey
  • Comforts of Home
  • Good Eats
  • Holiday Gift Guide 2010
  • Holiday Gift Guide 2
  • Good Eats 2
  • HMNS Pirates
  • The Future of Houston
  • We Heart Hou 2
  • Music Inspires
  • True Grit
  • Hoops City
  • Green Living 2011
  • Cruizin for a Cure
  • Summer Fun 2011
  • Just Beat It
  • Real Estate 2011
  • Shelby on the Seine
  • Rx in the City 2011
  • Entrepreneur Video Series
  • Going Wild Zoo
  • State of the Arts 2011
  • Fall for Fashion 2011
  • Elaine Turner 2011
  • Comforts of Home 2011
  • King Tut
  • Chevy Girls
  • Good Eats 2011
  • Ready to Jingle
  • Houston at 175
  • The Love Month
  • Clifford on The Catwalk Htx
  • Let's Go Rodeo 2012
  • King's Harbor
  • FotoFest 2012
  • City Centre
  • Hidden Houston
  • Green Living 2012
  • Summer Fun 2012
  • Bookmark
  • 1987: The year that changed Houston
  • Best of Everything 2012
  • Real Estate 2012
  • Rx in the City 2012
  • Lost Pines Road Trip Houston
  • London Dreams
  • State of the Arts 2012
  • HTX Fall For Fashion 2012
  • HTX Good Eats 2012
  • HTX Contemporary Arts 2012
  • HCC 2012
  • Dine to Donate
  • Tasting Room
  • HTX Comforts of Home 2012
  • Charming Charlie
  • Asia Society
  • HTX Ready to Jingle 2012
  • HTX Mistletoe on the go
  • HTX Sun and Ski
  • HTX Cars in Lifestyle
  • HTX New Beginnings
  • HTX Wonderful Weddings
  • HTX Clifford on the Catwalk 2013
  • Zadok Sparkle into Spring
  • HTX Let's Go Rodeo 2013
  • HCC Passion for Fashion
  • BCAF 2013
  • HTX Best of 2013
  • HTX City Centre 2013
  • HTX Real Estate 2013
  • HTX France 2013
  • Driving in Style
  • HTX Island Time
  • HTX Super Season 2013
  • HTX Music Scene 2013
  • HTX Clifford on the Catwalk 2013 2
  • HTX Baker Institute
  • HTX Comforts of Home 2013
  • Mothers Day Gift Guide 2021 Houston
  • Staying Ahead of the Game
  • Wrangler Houston
  • First-time Homebuyers Guide Houston 2021
  • Visit Frisco Houston
  • promoted
  • eventdetail
  • Greystar Novel River Oaks
  • Thirdhome Go Houston
  • Dogfish Head Houston
  • LovBe Houston
  • Claire St Amant podcast Houston
  • The Listing Firm Houston
  • South Padre Houston
  • NextGen Real Estate Houston
  • Pioneer Houston
  • Collaborative for Children
  • Decorum
  • Bold Rock Cider
  • Nasher Houston
  • Houston Tastemaker Awards 2021
  • CityNorth
  • Urban Office
  • Villa Cotton
  • Luck Springs Houston
  • EightyTwo
  • Rectanglo.com
  • Silver Eagle Karbach
  • Mirador Group
  • Nirmanz
  • Bandera Houston
  • Milan Laser
  • Lafayette Travel
  • Highland Park Village Houston
  • Proximo Spirits
  • Douglas Elliman Harris Benson
  • Original ChopShop
  • Bordeaux Houston
  • Strike Marketing
  • Rice Village Gift Guide 2021
  • Downtown District
  • Broadstone Memorial Park
  • Gift Guide
  • Music Lane
  • Blue Circle Foods
  • Houston Tastemaker Awards 2022
  • True Rest
  • Lone Star Sports
  • Silver Eagle Hard Soda
  • Modelo recipes
  • Modelo Fighting Spirit
  • Athletic Brewing
  • Rodeo Houston
  • Silver Eagle Bud Light Next
  • Waco CVB
  • EnerGenie
  • HLSR Wine Committee
  • All Hands
  • El Paso
  • Houston First
  • Visit Lubbock Houston
  • JW Marriott San Antonio
  • Silver Eagle Tupps
  • Space Center Houston
  • Central Market Houston
  • Boulevard Realty
  • Travel Texas Houston
  • Alliantgroup
  • Golf Live
  • DC Partners
  • Under the Influencer
  • Blossom Hotel
  • San Marcos Houston
  • Photo Essay: Holiday Gift Guide 2009
  • We Heart Hou
  • Walker House
  • HTX Good Eats 2013
  • HTX Ready to Jingle 2013
  • HTX Culture Motive
  • HTX Auto Awards
  • HTX Ski Magic
  • HTX Wonderful Weddings 2014
  • HTX Texas Traveler
  • HTX Cifford on the Catwalk 2014
  • HTX United Way 2014
  • HTX Up to Speed
  • HTX Rodeo 2014
  • HTX City Centre 2014
  • HTX Dos Equis
  • HTX Tastemakers 2014
  • HTX Reliant
  • HTX Houston Symphony
  • HTX Trailblazers
  • HTX_RealEstateConfidential_2014
  • HTX_IW_Marks_FashionSeries
  • HTX_Green_Street
  • Dating 101
  • HTX_Clifford_on_the_Catwalk_2014
  • FIVE CultureMap 5th Birthday Bash
  • HTX Clifford on the Catwalk 2014 TEST
  • HTX Texans
  • Bergner and Johnson
  • HTX Good Eats 2014
  • United Way 2014-15_Single Promoted Articles
  • Holiday Pop Up Shop Houston
  • Where to Eat Houston
  • Copious Row Single Promoted Articles
  • HTX Ready to Jingle 2014
  • htx woodford reserve manhattans
  • Zadok Swiss Watches
  • HTX Wonderful Weddings 2015
  • HTX Charity Challenge 2015
  • United Way Helpline Promoted Article
  • Boulevard Realty
  • Fusion Academy Promoted Article
  • Clifford on the Catwalk Fall 2015
  • United Way Book Power Promoted Article
  • Jameson HTX
  • Primavera 2015
  • Promenade Place
  • Hotel Galvez
  • Tremont House
  • HTX Tastemakers 2015
  • HTX Digital Graffiti/Alys Beach
  • MD Anderson Breast Cancer Promoted Article
  • HTX RealEstateConfidential 2015
  • HTX Vargos on the Lake
  • Omni Hotel HTX
  • Undies for Everyone
  • Reliant Bright Ideas Houston
  • 2015 Houston Stylemaker
  • HTX Renewable You
  • Urban Flats Builder
  • Urban Flats Builder
  • HTX New York Fashion Week spring 2016
  • Kyrie Massage
  • Red Bull Flying Bach
  • Hotze Health and Wellness
  • ReadFest 2015
  • Alzheimer's Promoted Article
  • Formula 1 Giveaway
  • Professional Skin Treatments by NuMe Express

    Knowledge Rules

    The top 5 things I learned while getting high at the Up Experience

    Joel Luks
    Oct 30, 2013 | 12:35 pm

    I got high at the Up Experience. Not from sniffing smelly markers or from imbibing purple drank, but from a barrage of nonstop are-you-serious intel that blows your mind and reframes how you view the world.

    The yearly, daylong conference, held at the Stafford Centre, hosts some dozen speakers of global repute who share their latest research in fields ranging from education, medicine, technology, philanthropy and current events. These influentials are the innovators of today — among them are authors, doctors, inventors, researchers, business leaders and entrepreneurs — who collectively have the pulse on current trends that predict the future.

    It's an impossible task to capture every detail, thought and statistic that was shared in each 20-minute presentation. Instead, below find my top five things that will surely remain ingrained in my gray matter — for better or for worse.

    Cyber Blackmail

    Why do criminals rob banks? Simply put, because of economies of scale, as in more loot in one hit.

    It's the rationale for infamous train robberies of yesteryear, and it's the impetus behind the growth of global Internet no-nos. Criminologist and author Marc Goodman estimates that 600,000 people are cyber hacked every day.

    I f you control the code, you control the world. More connections equals more vulnerability.

    Take the Chinese government, for example, which employs more than 3,000 tech geeks to infiltrate firewalls. Blackmail and extortion is big business. In Japan, users of child pornography platforms were threatened with revealing their identities if they didn't fork over large sums of cash. Nevertheless, Goodman warns against attributing virtual misdeeds to international espionage activities.

    Let's not forget why Julian Paul Assange and Edward Snowden gained notoriety in the first place.

    Lesson learned? If you control the code, you control the world. More connections equals more vulnerability. The solution, Goodman proposes, is crowdsourced security, because public safety is too important to leave it only to the professionals.

    The doctor will see you know, her name is Siri

    The modern version of a practicing physician is a dying vocation, posits Dr. Eric Topol. Whereas the general practice of medicine has concentrated on creating protocols that affect the masses, a revolution that has increased the use bio sensors attached to personal mobile devises has the potential to focus on the individual.

    Cars have more than 400 sensors, cellphones have more than 10. Imagine what can happen if personal objects like necklaces, gloves and socks had sensors that could measure vital signs? Diagnose an ear infection via apps? Even predict a heart attack days in advance?

    The future is now. Mobile phone imaging capabilities are in use. Topol predicts that science data analysts will rule the medical industry of tomorrow.

    Your body cannot lie

    There's no fooling former CIA agent, body language expert and author Janine Driver, who can read body language to uncover the hidden stories behind casual, matter of fact statements. Driver, however, advises not to assume that gestures such as shoulder shrugs and half smiles or smirks indicate that a lie has just been told. Instead, automatic responses disclose that there's information withheld. Don't settle for the first response. Ask follow-up questions.

    Driver's tip to look secure and powerful: Adopt the Steve Jobs pose, make a fist and rest it below your chin.

    Charity Paradox

    "We have a visceral reaction to the idea that anyone would make very much money helping other people," Dan Pallotta says. "Interesting that we don't have a visceral reaction to the notion that people would make a lot of money not helping other people."

    Pallotta speaks of what nonprofit organizations label as "overhead," the ratio of administrative costs in comparison to dollars that directly benefit a cause. Two percent of country's gross domestic product is donated to charity, a number that hasn't increased since it began being measured in 1970.

    How can the nonprofit sector grow if it isn't "allowed" to compensate their leaders competitively, if advertising dollars are limited and if risk-taking is frowned upon? If you prohibit failure, you kill innovation — something that's true in any endeavor.

    Leave children alone and they will learn

    Sugata Mitra, professor of educational technology at Newcastle University in the United Kingdom, studied how children interact with unknown objects when left unattended. When a computer was installed in a public space in a rural village in India, his research shows that in nine months children's computer literacy grew to the same level as a typical secretary in more developed societies.

    Mitra says that groups of children can learn most things on their own, something that's readily evident in wunderkind Jack Andraka, who at age 15 devised a test for the early detection of pancreatic, ovarian and lung cancer.

    Andraka, now 16, inspired by the loss of a close family friend, began his journey with Google searches and Wikipedia articles, but found difficulty in accessing information guarded by pay walls that inhibit the free flow of information, particularly scientific journals. If institutions such as Harvard University can't afford the cost of publishing journals, the price is steep for curious minds who have the ability to change the world.

    And what have you done lately, may I ask?

    The Up Experience hosts some dozen speakers of global repute who share their latest research in fields ranging from education, medicine, technology, philanthropy and current events.

    The UP Experience, crowd, auditorium, Stafford Performing Arts Theatre
    The UP Experience Facebook
    The Up Experience hosts some dozen speakers of global repute who share their latest research in fields ranging from education, medicine, technology, philanthropy and current events.
    unspecified
    news/innovation

    most read posts

    Beloved Houston Italian restaurant bids farewell and more top stories

    H-E-B's new store brings strawberry cups and seafood boils to Katy

    Washington Avenue's drive-thru only Chick-fil-A sets opening date

    brain scientists at work

    Rice University scientists invent new algorithm to fight Alzheimer's

    Jef Rouner
    Oct 24, 2025 | 3:00 pm
    Vicky Yao and Qiliang Lai of Rice University work on a laptop.
    Photo courtesy of Rice University
    Vicky Yao, an assistant professor of computer science and member of the Ken Kennedy Institute at Rice University, and Qiliang Lai, a Rice postdoctoral researcher

    A new breakthrough from researchers at Rice University could unlock the genetic components that determine several human diseases such as Parkinson's and Alzheimer's.

    Alzheimer's disease affected 57 million people worldwide in 2021, and cases in the United States are expected to double in the next couple of decades. Despite its prevalence and widespread attention of the condition, the full mechanisms are still poorly understood. One hurdle has been identifying which brain cells are linked to the disease.

    For years, it was thought that the cells most linked with Alzheimer's pathology via DNA evidence were microglia, infection-fighting cells in the brain. However, this did not match with actual studies of Alzheimer's patients' brains. It's the memory-making cells in the human brain that are implicated in the pathology.

    To prove this link, researchers at Rice alongside Boston University developed a computational algorithm called “Single-cell Expression Integration System for Mapping genetically implicated Cell types," or SEISMIC. It allows researchers to zero in on specific neurons linked to Alzheimer's, the first of its kind. Qiliang Lai, a Rice doctoral student and the lead author of a paper on the discovery published in Nature Communications, believes that this is an important step in the fight against Alzheimer's.

    “As we age, some brain cells naturally slow down, but in dementia ⎯ a memory-loss disease ⎯ specific brain cells actually die and can’t be replaced,” said Lai. “The fact that it is memory-making brain cells dying and not infection-fighting brain cells raises this confusing puzzle where DNA evidence and brain evidence don’t match up.”

    Studying Alzheimer's has been hampered by the limitations of computational analysis. Genome-wide association studies (GWAS) and single-cell RNA sequencing (scRNA-seq) map small differences in the DNA of Alzheimer's patients. The genetic signal in these studies would often over-emphasize the presence of infection fighting cells, essentially making the activity of those cells too "loud" statistically to identify other factors. Combined with greater specificity in brain regional activity, SEISMIC reduces the data chatter to grant a clearer picture of the genetic component of Alzheimer's.

    “We built our seismic algorithm to analyze genetic information and match it precisely to specific types of brain cells,” Lai said. “This enables us to create a more detailed picture of which cell types are affected by which genetic programs.”

    Though the algorithm is not in and of itself likely to lead to a cure or treatment for Alzheimer's any time soon, the researchers say that SEISMIC is already performing significantly better than existing tools at identifying important disease-relevant cellular signals more clearly.

    “We think this work could help reconcile some contradicting patterns in the data pertaining to Alzheimer’s research,” said Vicky Yao, assistant professor of computer science and a member of the Ken Kennedy Institute at Rice. “Beyond that, the method will likely be broadly valuable to help us better understand which cell types are relevant in different complex diseases.”

    rice universityscienceresearch
    news/innovation
    CULTUREMAP EMAILS ARE AWESOME
    Get Houston intel delivered daily.
    Loading...